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The Unimouse can be adapted to each user’s personal needs, thus offering a high degree of ergonomic comfort. A highlight is the thumb support movable along three axes, on which the thumb can rest in a relaxed way. The hand-rest surface may be tilted by 70 degrees and thus allows for a natural hand position. The four adjustments are equipped with a friction mechanism facilitating operation and guaranteeing stability of the mouse in any position.